im not saying that setting up whilst stood still isnt the way
what im saying and im sure you`ll agree is that the bike spends most of it`s time out on the road and that the engine is therefore under load most of the time, which is where "IF any" damage will occour.
once off tick over at approx 1/4 throttle the mixture is controlled by the needle untill it reaches approx 3/4 throttle where it is then controlled by main jet and the air volume available ie: air filter restrictions so yes although basic mixture is set at tick over etc moderate and 3/4 throttle is where the engine spends most of its cycle
unless your a power ranger n just pose at the local cafe
now without using dyno`s n rolling road set-ups which i doubt most owners don`t have in there shed
i`m purely giving an easy way that most owners can do very easily with a screwdriver and a plug spanner and does`nt cost anything and help the owner learn abit about there ride .