Mate of mine bought a Toyota Celica new in 2001.
He never had it serviced....ever, just kept adding oil when it needed it.
It did around 130,000 miles before it finally packed in.
In any event someone gave him a replacement set of plugs, and he changed them (at this point the car had done 120,000 miles ish).
I asked him was the car running better now it had a new set of plugs; he replied that he couldn't tell any difference.